An Overview of Nanostructured Lipid Carriers and Its Application in Drug Delivery through Different Routes

Nanostructured Lipid Carriers (NLC) are nano-sized colloidal drug delivery system that contains a lipid mixture consisting of both solid and liquid lipids in their core. This Lipid-Based Nanosystem is introduced as biocompatible, non-toxic, safe nano-drug compared to polymeric or metallic nanoparticles. Due its safety, stability, high loading capacity other lipid-based nanocarriers, NLC gained the attention researchers formulate effective carriers. The ability increase solubility permeability while encapsulating lipidic shell makes them an ideal carrier for through difficult-to-achieve routes. Surface modification use various additives result targeting increased residence time. With such qualities, NLCs can be used treat variety diseases cancer, infections, neurodegenerative diseases, hypertension, diabetes, pain management. review focuses on recent developments being made deliver drugs genes different routes via these nanocarriers. Here, we also discuss about historical background, structure, types commonly employed techniques manufacturing